Neupro - Treating Parkinson's disease
What is Parkinson's disease?
Parkinson's disease is a disorder of the central nervous system. There are approximately 4 million patients across the world suffering from this pitiable condition.
Tremor, rigidity of muscles, tiredness, depression, difficulties with balance and handwriting, speech and facial expression changes, difficulties with eating and swallowing are some of the symptoms of Parkinson's disease. Neupro is the first approved treatment for this debilitating disease.
How Neupro works?
The levels of dopamine fall in the body after the age of 50 in most people due to Parkinson's disease.
The active ingredient in Neupro is rotigotine which belongs to the class of medications called dopamine agonist. Rotigotine in Neupro imitates the action of dopamine which is found in the central nervous system and is responsible for co-ordination and control of movements.
Neupro delivers a measured dose of rotigotine over a period of 24 hours to help maintain the necessary level of dopamine in the body and thereby reduce the disconcerting effects of the disease.
Neupro clinical trials
The effectiveness of Neupro was demonstrated in one fixed-dose response study and two flexible-dose studies.
Neupro was clinically tested in two parallel groups' randomized, double-blinded, placebo-controlled studies involved 1,154 patients with early Parkinson's who were not on other anti-Parkinson's agents.
Patients on Neupro showed an immediate reduction in scores on the Unified Parkinson's Disease Rating Scale (UPDRS) of about seven points and after six months the score remained four points below baseline.
Side effects of Neupro
Neupro is generally well tolerated. The most common side effects of Neupro in clinical trials included patch-site skin reactions, dizziness, nausea, vomiting, drowsiness and insomnia. Other side effects of Neupro are narcolepsy-like sleep attacks, hallucinations, and postural hypotension.
Apply Neupro patches at same time each day for best results.
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